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Side Effects Several physical, mental, and emotional changes are possible with testosterone therapy, such as: Redistribution of weight from thighs and hips to the abdomen Increased muscle mass Changes in facial features (such as the appearance of a more angled jawline) Deepened voice, vocal pitch Increased libido A different range of emotions Changes in clitoral size and length Shortened or absent menstruation Alternatives If GAHT alone does not achieve its desired goals, surgical intervention may be considered