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Drugs in this class include: Semaglutide (marketed, among others, under the name Ozempic for the treatment of diabetes, and Wegovy for weight management)
Regardless of whether or not you belong to one of these two groups, I cannot emphasize enough the importance of following a heart healthy dietary pattern, exercising regularly, not smoking, getting adequate sleep and knowing your numbersblood pressure, cholesterol and sugar levels
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To inactivate LS GLP-1R neurons, we injected AAV expressing double-floxed EGFP and TeNT (AAV-DIO-EGFP-2A-TeNT) into the bilateral LS of GLP-1R-ires-Cre mice to achieve specific expression of EGFP-2A-TeNT in LS GLP-1R neurons (Figure 3A and Supplemental Figure 6C)
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