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The inherent mesoporosity of the Cu-MBGN particles is in the range of 310 nm and below the limit of detection of the nano-CT

The molecular intricacies of ferroptosis are elucidated in Fig

Cardiac MRI showed no evidence of myocardial (T2* = 45.5 ms) or hepatic (T2* = 17.5 ms) iron overload and normal bi-ventricular size and function, with LVEF of 66% and normal right ventricular ejection fraction of 63%

Vitamin D/vitamin D receptor (VDR) signaling intersects inflammation, oxidative stress/mitochondrial injury, fibrogenic pathways, the reninangiotensinaldosterone system (RAAS), and the gutkidney axis, providing a biologic rationale for renoprotection