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The protein migrates at approximately 8 kD in DTT reducing and non-reducing conditions by SDS-PAGE

(J Neurosci, 2007) This is mechanistically distinct from GHK-Cu's neurotrophin pathway and may make TB-500 relevant in demyelinating contexts, though this remains highly speculative without human trials

Free radicals and oxidative stress Oxidative stress is a result of an increase in the generation of free radicals or a decrease in the number of antioxidants

James investigation has additional implications for those with autism spectrum disorders: a severe deficiency in glutathione means poor ability to detoxify environmental toxins, particularly mercury