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Compouned Semaglutide works by mimicking a hormone naturally produced in your intestines known as GLP-1, according to the FDA

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Liraglutide attenuates high glucose-induced abnormal cell migration, proliferation, and apoptosis of vascular smooth muscle cells by activating the GLP-1 receptor, and inhibiting ERK1/2 and PI3K/Akt signaling pathways

GLP-1s help to reduce the impacts of chronic stress and help to alter food reward pathways in positive ways and may help reduce alcohol and other substance use disorders (Mozafarriun et al 2025)