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In the field of solid tumors, multi-target, multi-payload, and multi-modal combinations will help crack the code of resistance, whereas in the realm of autoimmune diseases, the exploration and application of customized solutions addressing immunogenicity and target complexity are expected to promote the precise clinical implementation of ADCs in non-malignant diseases

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The dosage of AOD9604 used in this study or 0.25 mg per injection, was carefully calculated to be molar equivalent to doses of full-length GH shown to be effective in prior rabbit OA studies