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Several genes involved in fatty acid synthesis and oxidation were altered in mice treated with anti-miR-122 including FAS, ACC1, and ACC2 84

Investigators are developing models to predict the efficacy of DPP-4 inhibitors, GLP-1 RAs, SGLT-2 inhibitors, sulfonylureas, and thiazolidinediones to lower HbA1c levels using widely available clinical features (age, duration of diabetes, sex, baseline HbA1c, BMI, estimated glomerular filtration rate, HDL cholesterol, total cholesterol, and alanine aminotransferase) to facilitate therapy (14)

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How should clinicians monitor patients on GLP1 therapy