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Thorax 1997;52:289-90

Full text: Loguercio, C., & Di Pierro, M

Benefits of Using Salicylic Acid for Acne Scars Lightens dark marks and hyperpigmentation Smoothens uneven and rough skin texture Unclogs pores and prevents new breakouts Reduces redness, swelling, and inflammation Improves skin tone, clarity, and radiance Promotes long-term healthy, clear skin Possible Side Effects and Safety Tips Although generally safe for most skin types, overuse of salicylic acid can cause: Dryness or flakiness Mild redness or irritation Temporary peeling Tip: Always pair salicylic acid with a hydrating moisturizer and avoid layering it with other exfoliating acids or retinoids on the same day

As a consequence, although clinical application of PAC may be considered as safe, in the case of severely depleted GSH levels PAC should be administered with caution, especially in subjects with severe GSH depletion who, again, are those at higher risk of developing severe COVID-19 disease