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People with higher levels of oxidative stress or lower baseline glutathione may notice more dramatic benefits from supplementation compared to those with already-optimal levels

In a 2022 study, scientists concluded that MOTS-c plays an essential physiological role in mitochondrial function and appears to be a promising therapy for [ME/CFS] associated fatigue. This means MOTS-c could potentially help restore cellular energy production in conditions where it is deficient, thereby improving stamina and reducing chronic fatigue

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