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Mechanistically, niacin enhances blood flow (via vasodilation), supports neuronal energy demands, and helps maintain cellular resilience under stress

Without DAC Lets clear this up once and for all, because it's a formidable point of confusion that can derail an entire research project

One spillover effect could be an increase in productivity, Hatzius said, citing academic studies that found obese individuals are less likely to work and to be less productive at work "These estimates therefore suggest that obesity-related health complications subtract over 3% from per-capita output, implying an over 1% hit to total output when combined with the over 40% incidence of obesity in the US population," Hatzius said

Blood 130:22372237 Akhter MS, Hamali HA, Rashid H, Dobie G, Madkhali AM, Mobarki AA, Oldenburg J, Biswas A (2023) Mitochondria: emerging consequential in sickle cell disease