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In a recent report Bateman et al (2013) reported the ability of aspirin to acetylate 120 proteins in HCT15 human adenocarcinoma cells using an alkyneaspirin chemical reporter

The "clinical reports" circulating in patient communities are anecdotal

Curcumin enhances the activity of Phase I and Phase II hepatic detoxification enzymes, accelerates fatty acid oxidation, and increases mitochondrial energy output

16 A 2021 meta-analysis of semaglutide RCTs found no association with increased DR risk when all trials were combined, although this result did not reach statistical significance