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When to Contact Your Doctor Contact your healthcare provider immediately if you experience: severe or persistent abdominal pain, persistent vomiting or diarrhea (dehydration risk), inability to keep food or fluids down for 24+ hours, signs of pancreatitis (severe upper abdominal pain radiating to back), or any symptoms that significantly impact your daily life

Clinical trials such as the STEP programme have examined body composition changes with treatment

In a previous paper we have demonstrated MAHT at 8 mg induces a significant reduction in serum IgE and HLA-DR expression in PBMC, together with a modulation in CD3 + , CD4 + and CD8 + lymphocyte subpopulations (39)

Several drugmakers are developing weekly injections or daily pills, but some haven't ruled out testing less frequent dosing for their drugs