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MS analyses were performed in the positive ESI and high resolution mode with the instrument setting for the capillary voltage (+2.5 kV), sampling cone (50 V), source temperature (120 C), desolvation temperature (450 C), cone gas (10 L/h) and desolvation gas (850 L/h) given in parenthesis

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Second, for localized applications (the most common use case), your focus must shift from dosing frequency to formulation