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In the methylation cycle, B12 helps convert homocysteine into methionine, a crucial step for maintaining healthy homocysteine levels and promoting DNA repair, immune function, and neurotransmitter production

Spirulina has the potential to be used as an adjuvant supportive agent in the treatment of inflammatory bowel disease (110)

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The duration, timing, and cyclic-nature of pineal melatonin production, as well as its seasonal variation according to photoperiod changes, contribute to the temporal organization of physiological phenomena into circadian and circannual timescales ( eigen-zeitgeber action (i.e., being an internal temporal cue) or seasonal effect resulting from these sources