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This process, known as lipolysis, allows fat cells to release stored energy that the body can use as fuel

In contrast, gastrointestinal (GI) toxicity tends to be more frequent at lower doses of cyclophosphamide in SLE, likely due to its non-linear pharmacokinetic profile, which results in greater biliary excretion of toxic metabolites following low-dose administration compared to high-dose administration (Zhong et al., 2006)

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