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7 Conclusions and perspectives In recent years, with the increasing exploration of the intestinal microenvironment, there is growing evidence that dysbiosis of the gut microbiota and disorders of iron metabolism are closely associated with the onset and progression of IBD

This may be attributed to the increased sensitivity of the digestive system and the use of concomitant drugs in patients with diabetes mellitus

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At spacings of four or more residues the energetics of binding are relatively stable