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No improvements were seen in OAP or YAG

9 The development of ferroptosis-focused Chinese medicine for the treatment of depression and atherosclerosis 9.1 Treatment of atherosclerosis with a Chinese medicine monomer targeting ferroptosis Paeonia lactiflora, a medicinal herb native to China, is the source of Paeonol (Pae), a bioactive compound with potent antioxidant and lipid-lowering properties (Shi et al., 2020)

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Receptor Saturation and Additive Effects Because both peptides act at the same receptor, their combined effect is likely additive rather than synergistic in the pharmacological sense