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Vitamin B12 is integral to the synthesis of DNA, necessary for cell division and the creation of new cells

Treatment duration proves critical variable where longer courses create more durable changes - users completing 2-3 month treatments typically maintain 20-40% of peak benefits long-term, 4-6 month treatments sustain 40-60% of improvements, and 6-12+ month courses preserve 50-70% of maximum benefits potentially indefinitely

In FM, altered methylation patterns have been observed, leading to changes in gene expression that contribute to the development and maintenance of chronic pain [68]

If you suspect you may have kidney disease or are at risk for developing it, talk to your doctor