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Nrf2 activation regulates antioxidant responses to modify cellular redox states from predominantly pro-oxidant to antioxidant, and, in an antioxidant environment, macrophage phenotypes shift from M1 pro-inflammatory to M2 anti-inflammatory, reducing the probability of cytokine storms, ARDS, and lethality (Tan et al., 2016

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The pellets were resuspended by addition of 90 l of buffer containing urea (8 M), TCEP (5 mM) and Triethylammonium bicarbonate (TEAB, 50 mM, pH 8.5) with sonication

Temperature is considered a major factor affecting both quality and the enzyme -glutamyl transpeptidase ( -GTP), which regulates SAC formation