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The 16S rRNA sequencing data have been deposited with links to BioProject accession number PRJNA990939 (ABX) and PRJNA1039541 (selective antibiotic treatment) in the NCBI BioProject database ( GLP-1 concentration detection Blood was collected by cardiac puncture from the isoflurane-anesthetized mice and placed in the serum isolation tube (Sarstedt) with 10 l DPP4 inhibitor (Millipore)

The relevance of the microbiota in the development of the central nervous system has been well demonstrated by previous studies using GF animals

Aljabari B, Calogero AE, Perdichizzi A, et al