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Description

Semaglutide 2.4 mg once weekly is the latest approved GLP-1 RA for obesity management (2021) and results in 1517% mean WL through appetite reduction [11, 12]

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In the intracellular pathway, drugs are internalized by olfactory neurons through endocytosis, transported to the end of the axon, and subsequently released into the brain via exocytosis (Crowe et al., 2018)

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Science 1973, 182: 929-931

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