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Two different objects were applied in the training phase: the LEGO bricks (8 3.5 cm) and Falcon tissue culture flask filled with sand (9.5 5.5 2.5 cm)

Natural killer cytotoxicity - the ability of NK cells to kill target cells such as those infected by viruses - also increased by more than two-fold compared to placebo

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Nail involvement is more widely associated with extensive forms (total or universal) and is considered a poor prognostic factor.9 Treatment should be directed toward controlling the systemic disease and includes oral corticosteroids, although there is still no consensus regarding the most appropriate type or dosage.12 Other therapeutic alternatives include immunosuppressants such as methotrexate, cyclosporine, or azathioprine, and more recently JAK inhibitors, which have shown good results for both hair and nails.13,32 Nail involvement in atopic dermatitis (AD) The periungual skin often presents erythema, edema, and scaling