Other typical agents with reported inhibitory activities on TYR include kojic acid (111,112), methyl gentisate (113,114), ganodermanondiol (71,115), 10-hydroxy-2-decenoic acid (116), Stichopus japonicus extracts (69) and bis (4-hydroxybenzyl)sulphide (117)
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Time of ingestion: If time of ingestion is unknown, assume that it took place at the earliest possible time, to give the worst-case scenario
Nesse contexto, o drug delivery no se refere a vias invasivas, mas sim a mtodos que potencializam a ao local do ativo por meio do contato direto com a pele, respeitando sua fisiologia e os limites regulatrios