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Diabetologia 59:13721375 Liang Y, Osborne MC, Monia BP et al (2004) Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db / db mice

It appears to represent a recalibration of the brain's reward and satiety circuitry, reducing the hedonic drive to eat independently of hunger signals

All authors have read and approved the content of the manuscript, and there are no other relevant factors that could affect the objectivity of the research

Adults aged 40 to 60 years had higher odds for receiving a novel diabetes drug than those younger than 40 years (OR = 1.81