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Non-bolded entries reflect metabolites and pathways supported primarily by animal model evidence, where causal roles in human DKD remain to be prospectively validated

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A simple timing framework: Eat within 1 to 2 hours of waking with a protein focus Space meals 4 to 5 hours apart Dont leave more than 5 to 6 hours between protein sources during waking hours Have a protein-anchored option available as a backup snack This framework is flexible enough to work around variable appetite and side effects while maintaining enough consistency to protect lean mass protection during fat loss

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