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A recent study demonstrated the protective role of GLP-1R receptors against hyperglycemia- induced endothelial to-mesenchymal transformation which is a crucial component of diabetic endothelial injury in cardiomyopathy, nephropathy, and retinopathy

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Furthermore, histological examination revealed that melasma skin is thicker, more curled, and contain more fragmented elastic fibers in comparison to normal skin (Rajanala et al., 2019a)

In addition to being associated with increased cardiovascular (CV) risk, T2DM may influence the choice of multiple treatments for CAD