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it is an endogenous fragment, and one line of thinking holds that it may be liberated from larger proteins for example, during tissue injury when extracellular-matrix proteins such as collagen and SPARC (osteonectin) are proteolytically degraded
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The low-MW fractions are pushed through the channels into the dermis, where they engage CD44 receptors on fibroblasts and contribute to volumetric hydration in deeper layers
This lengthy timeline frustrated customers who needed more immediate support for antioxidant support during periods of increased demand on their bodies
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