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This includes active joint infection, severe infections in the target area, bleeding disorders that increase procedural risks, and known hypersensitivity to hyaluronic acid products
Cardiovascular manifestations evolve from hypertension and tachycardia to myocardial depression, profound bradyarrhythmias, widened QRS complexes, and refractory ventricular fibrillation if plasma levels exceed roughly 10 g/mL
It creates a solution that is relatively concentrated, which can be useful for many research protocols
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