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The remainder had a confirmed genetic cause including patients with contiguous deletions of TNXB and CYP21A2 , 3,6,7 whole TNXB gene deletions, and intragenic homozygous and compound heterozygous pathogenic variants

Summary The knowns Allulose can be considered as safe for human use and that is also represented by the generally recognized as safe status and safe use in a number of countries

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Notably, no signal for ION was detected with tirzepatide, a dual GLP-1/GIP receptor agonist used for diabetes and obesity, and comparator drugs such as metformin and insulin also showed no significant associations