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You might wonder how a pill works if you lack intrinsic factor: at very high oral doses, a small amount of B12 can be absorbed directly through the gut wall via passive diffusion, bypassing the need for intrinsic factor entirely [1] [3]

Pre-clinical work across skin, lung, liver, and bone models has reported tissue-repair activity, attributed to fibroblast restoration, antioxidant signaling, anti-inflammatory effects, and matrix-protein synthesis

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