Wegovy is FDA-approved for chronic weight management in combination with diet and exercise for: Adults with obesity (with a BMI of 30 or higher) Adults who are overweight (with a BMI of 27 or higher) with at least one weight-related condition such as heart disease, high blood pressure, sleep apnea, or type 2 diabetes, Adolescents 12 years of age and older with an initial BMI at or above the 95th percentile for age and sex Wegovy is also FDA-approved for reducing the risk of serious cardiovascular problems like heart attack in adults with obesity or overweight
doi: 10.1016/j.arr.2024.102248 60 ZhouXChenZXiaoLZhongYLiuYWuJet al
Skipping steps or jumping to higher concentrations increases nausea, gastrointestinal side effects, and potential for inadequate titrationmaking step-wise progression medically sound practice rather than arbitrary delay
Bae JH, Bassenge E, Kim KB, Kim YN, Kim KS, Lee HJ, Moon KC, Lee MS, Park KY, Schwemmer M: Postprandial hypertriglyceridemia impairs endothelial function by enhanced oxidant stress