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In signaling studies using cell lines expressing GIPR or GLP-1R, tirzepatide demonstrated similar potency to GIP in activating GIPR (EC50 = 22.4 pM for tirzepatide vs

Dapagliflozin added to usual care in individuals with type 2 diabetes mellitus with pre-existing cardiovascular disease: a 24-week, multicenter, randomized, double-blind, placebo-controlled study with a 28-week extension

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