(Naltrexone is also used in alcohol use disorder.) But there's currently no other drug on the market that would do what GLP-1 drugs appear to do prevent risk of addiction more generally
Nonetheless, a decrease in PI3K, Akt, mTOR, proliferation, migration, invasion, p-ERK1/2, growth, colony formation, and inflammation represented by nuclear factor B (NF-B) expression, cell viability, and an overall decrease in proliferation was noted with applying liraglutide (Table 1)
Cardiovascular disease and CKD In 2024, semaglutide was approved by the FDA as the first weight-loss medication to reduce the risk of major adverse cardiovascular events (MACE) in adults with obesity or who are overweight, without T2D and stablished CVD, when prescribed with a reduced-calorie diet and increased physical activity
GLP-1: physiological effects and potential therapeutic applications