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The study, which evaluated data from more than 100,000 diabetes patients, found that those taking GLP-1s were upwards of 68 times more likely to develop NAION than those using other treatment methods

Adding glucagon means the medication can bind not only to GLP-1 and GIP receptors (and mimic the actions of these hormones) but also to glucagon receptors

9,10 This could be attributed to natriuresis and the improved function of the vascular endothelium facilitated by the release of nitric oxide

Your TSH and free T4 should be checked every 68 weeks during the first 34 months of semaglutide use, then every 3 months thereafter