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Key highlights Although semaglutide is an effective medication, some patients consider its alternatives due to cost and insurance issues, persistent shortages, intolerable side effects, insufficient results, certain health conditions, or a preference for pills

These GLP-1 medications work by: delaying gastric emptying (which makes you feel full longer), decreasing appetite, blocking cravings, and increasing metabolism

Typically, the benefits can last about one week for individuals with a moderate deficiency

The gradual dose escalation protocol used in physician-supervised programs is designed specifically to minimize side effects