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In choosing add-on pharmacologic agents, a patient-centered approach is recommended that incorporates considerations for comorbidities, hypoglycemia risk, impact on weight, cost, risk of side effects, and patient preference [10]

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A Chinese oral drug at a fifth of that price undermines the entire margin structure on which the whole pipeline is builtand affects every investment case." Shah says, Revenue per patient drops 60 to 80 percent, and return on investment models built today at Rs2,000-plus collapse." He adds, however, that Rs500 to Rs800 pricing would require either a heavy market-capture subsidy strategy or a lower-efficacy molecule