DOI: Published online: February 13, 2026 1 Department of Internal Medicine, MedStar Washington Hospital Center, Washington, DC, USA 2 Georgetown University Medical Center, School of Medicine, Georgetown University, Washington, DC, USA 3 Department of Medicine, School of Medicine, Georgetown University, Washington, DC, USA 4 Department of Internal Medicine, School of Medicine, University of Jordan, Amman, Jordan 5 Department of Gastroenterology and Hepatology, INOVA Medical System, Leesburg, VA, USA Correspondence: Ahmad Abdulraheem Department of Internal Medicine, MedStar Washington Hospital Center, 110 Irving St NW, Washington, DC 20010 USA E-mail: [email protected] 2026 Korean Society of Gastrointestinal Endoscopy This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited
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Whereas the result of ACCORD must be interpreted carefully because it might have been influenced by the lack of statistical power for assessing cardiovascular events and the effects of baseline characteristics like statin or aspirin use, most of current guidelines generally do not recommend maintaining systolic blood pressure less than 120 mmHg to reduce mortality or cardiovascular disease other than stroke considering adverse events related to antihypertensive therapy, such as worsening renal function and electrolyte abnormalities
