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Many individuals with Hashimoto's thyroiditis experience weight gain as a consequence of reduced metabolic rate associated with hypothyroidism

Buteau J, Shlien A, Foisy S, Accili D: Metabolic diapause in pancreatic -cells expressing a gain-of-function mutant of the forkhead protein Foxo1

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Similarly, in primary cardiac fibroblasts, GLP-1R agonism inhibited TGF- signalling activity and expression of ECM proteins, including COL1A1 and COL3A1 [25]