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Exclusion Criteria Inability to give informed consent or comprehend study information

Taking ALA with food may reduce absorption, so it is generally recommended to take it at least 30 minutes before meals

anti-caking agents: vegetable magnesium stearate, silicon dioxide

Out of 19 studies comprising randomized clinical trials (RCTs), systematic reviews, and meta-analyses, 10 RCTs, both double-blind placebo-controlled and non-double-blind placebo-controlled, were included which were conducted on nutraceuticals primarily consisting of the bioactive components CoQ10 (ubiquinol), flavonoids, curcumin, and polyphenols in CKD patients to identify the renoprotective benefits of these bioactive components on the initial stages of CKD without displaying any kind of side effects in the participants