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Serious side effects of spironolactone Spironolactone has several potentially severe side effects: Severe hyperkalemia: As mentioned earlier, spironolactone can cause blood potassium levels to rise
2014;63:2985-3023;10.1016/j.jacc.2013.11.004 Garvey WT, Mechanick JI, Brett EM, et al
Why Side Effects Are Usually Worse at the Beginning The dose escalation schedule used with GLP-1 medications is specifically designed to reduce side effect burden by allowing the body time to adapt before the dose increases
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