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This receptor plays a central role in appetite regulation, energy homeostasis, and body weight control

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(Reuters) Known risk factors for NAION include: Diabetes High blood pressure High cholesterol Sleep apnea Smoking Medications that affect blood flow or circulation Because GLP-1 drugs influence metabolic function, blood sugar levels, and physiological processes that may affect circulation, plaintiffs in GLP-1 lawsuits allege that drug manufacturers knew or should have known about the potential risk of optic nerve damage and failed to adequately warn patients and healthcare providers