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Prolonged overdose of B6 (150-200 mg/day) over weeks can cause severe sensory-nervous-system dysfunction and ataxia.37 With normal usage serious adverse effects are not reported for pyridoxine (vitamin B6), however, diarrhoea, emesis and rosacea-like dermatitis may be observed in some cases (38)
Multiple systematic reviews show improvement in pain and function scores compared to hyaluronic acid and placebo injections
Keywords: Biologic therapies, Discogenic low back pain, Lumbar disc degeneration (LDD), Mesenchymal stem cells (MSCs), Platelet-rich plasma (PRP), Regenerative medicine, Rehabilitation integration I
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