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Both compounds act through copper ion coordination and share similar mechanisms VEGF upregulation, TGF-1 inhibition, collagen cross-linking

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36 It is noteworthy that most follow-up assessments in studies involving enamel matrix derivatives were conducted over a period of 1 year, whereas the follow-up duration in our trial was 6 months

The HGF/c-Met system is critical for neurogenesis, neuronal survival, neurite outgrowth, synaptic plasticity, and cerebroprotection, functions that significantly overlap with those attributed to AngIV