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The Polyvagal Theory in Therapy: Engaging the Rhythm of Regulation

The form of the peptide determines whether the exposure causes reversible or irreversible damage

The evaluation of patient preferences regarding oral versus injectable therapies could also be considered, as oral therapies can offer quality-of-life benefits through simplified administration (albeit with oral semaglutide requiring administration in a fasting state with 120 ml of water, followed by a post-dose fasting period of at least 30 min for optimum efficacy) and through shorter waiting times to initiation, with injectable antidiabetic therapies often associated with delays before patient training can be delivered through the NHS in the UK [19]

Escalante Muoz T, Rucavado Romero A, Fox JW et al (2011) Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases