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[1] [2] The severity of an overdose depends on several factors: The amount taken beyond the prescribed dose Individual patient characteristics (weight, concurrent medications) Timing of the last dose and whether other diabetes medications are being used Current blood glucose levels and recent food intake Gastrointestinal symptoms typically intensify with higher doses, as semaglutide's effect on gastric motility becomes more pronounced

Mina T, Yew YW, Ng HK, et al

It is advisable to avoid semaglutide if you have a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia syndrome type 2

Ancestral resurrection and directed evolution of fungal mesozoic laccases