UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency
The study included patients with obesity and knee osteoarthritis with trial endpoints examining weight loss and reduction in knee pain
doi: 10.2174/0113862073311197240425073859 Summary Keywords diabetic nephropathy, renal fibrosis, gut microbiota, short-chain fatty acids, traditional Chinese medicine, gutkidney axis, uremic toxins, butyrate Citation Jiang H, Wang X, Zhou W, Huang Z and Zhang W (2025) Gut microbiota-derived short-chain fatty acids mediate the antifibrotic effects of traditional Chinese medicine in diabetic nephropathy
Finally, they reflect pathways likely additional to those involved in the angiogenesis (Vukojevic et al., 2018), recently associated in particular with the increased expression, internalization of VEGFR2, and the activation of the VEGFR2-Akt-eNOS signaling pathway ( Genes Expression as Support ), given the rapid presentation of all of these effects, which occurred before the process of angiogenesis could be initiated (Sikiric et al., 1993