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& Hicks, C

7.1.2 Parkinsons disease PD is characterized by a gut-centered pathophysiology that parallels its CNS manifestations

Nevertheless, greater use of uricase knock-out animals and similar humanising paradigms may prove valuable in studying the interaction of UA with clinically relevant models of PD neurodegeneration

Some genotype-phenotype correlations have been identified in relation to GH secretion (116), but there is a lack of literature on the changes in the IGF system ( Table 3 )