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Final thoughts Stopping GHK-Cu typically produces gradual benefit decline over 2-4 months without dramatic rebound effects or rapid reversal to pre-treatment baseline, with 30-40% of long-term users (6+ months treatment) maintaining 50-70% of peak improvements indefinitely while shorter-term users show greater regression toward baseline
IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes
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