Mechanistic Comparison# Dosing Comparison# Amycretin Dosing# Amycretin dosing is investigational: Subcutaneous: Once-weekly injection, doses up to 60 mg studied in phase 1b/2a over 36 weeks Oral: Daily tablet, doses up to 50 mg (or 2 x 50 mg) studied in phase 1 Phase 2 T2D: Both subcutaneous and oral formulations studied over 36 weeks Phase 3 dose selection will be informed by the completed phase 2 data
Cario H, Smith DEC, Blom H, Blau N, Bode H, Holzmann K, et al
Common side effects may include: Mild injection-site reactions (redness, soreness, itching) Upset stomach or nausea Headache Mild anxiety or restlessness Rarely, allergic reactions If you experience difficulty breathing, severe dizziness, or hives, seek medical attention immediately
Administration: Most peptides are delivered via small subcutaneous injections, though some are available as oral capsules, creams, or nasal sprays