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Liver sinusoidal endothelial cells (LSECs) LSECs play a crucial role in maintaining liver homeostasis and regulating hepatic microcirculation [178]
BV has been shown to increase the expression and levels of several pro-apoptotic mediators, such as cytochrome C, Bcl-2-associated X protein (Bax), protein 53 (p53), Bcl-2 homologues antagonist/killer (Bak), caspase-3, caspase-9, and numerous death receptors while reducing the anti-apoptotic mediator Bcl-2 [37, 38, 52]
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Este enfoque permite reducir la demanda sobre el sistema antioxidante, favoreciendo un entorno en el que el organismo puede funcionar con mayor eficiencia
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